Honest comparison

A SelfDecode alternative for $49 instead of $499

SelfDecode is a big health platform sold in bundles from $499 to $899: more than 1,500 reports, a built-in AI coach and add-ons for conditions and medications. Helisoma is deliberately smaller and costs a tenth of the entry price: one wellness report for $49, parsed in your browser, and readable by the AI assistant you already use.

Free DNA analysis · $49 once for the full report · no subscription
Updated October 24, 2026. Prices checked on each company's own site.

What SelfDecode does well

Breadth and ambition. SelfDecode offers one of the largest consumer report libraries, more than 1,500 reports, uses polygenic scores that combine many variants, and has its own AI health coach. If you want one platform to keep advising you and the price fits, it is a serious product.

Where Helisoma is different

SelfDecodeHelisoma
PricingBundles from $499 to $899$49 once, free analysis first, no subscription
Your raw DNA fileUploaded and stored on their serversRead in your browser, never uploaded
Findings style1,500+ reports with in-platform recommendationsA curated set of replicated findings, each stating its effect size honestly
Works with your AITheir own built-in AI coachConnects to Claude and ChatGPT live, pairs with Gemini and Whoop Coach
Where advice livesInside their platformIn your own AI chat, grounded in your report

Which one should you pick?

Pick SelfDecode if you want an all-in-one platform with the biggest report library and its own AI coach, and $499 or more fits your budget.

Pick Helisoma if you want the findings that replicate for $49, with your raw file on your own device and coaching through the AI you already talk to every day instead of another app.

Also comparing? We compare against Promethease, Genomelink, Nebula Genomics, Genetic Lifehacks, Xcode Life and Sequencing.com.

Questions people ask

Do I have to upload my raw DNA file to Helisoma?

No, and that is the core difference. Your browser reads the file on your own device and sends only the small set of markers the report uses. We never receive or store the raw file.

What does the Helisoma report cover?

Sleep and chronotype, caffeine response, nutrition markers, training and recovery, stress and mood leans, and longevity markers. Every card shows your genotype, the honest effect size, and a link to the study behind it.

How much does Helisoma cost?

The analysis is free: drop your raw DNA file on helisoma.com and see real insights with no account. The full report is a one-time $49 payment with no subscription.

Is Helisoma a medical test?

No. It is an educational wellness report built on peer-reviewed population research, not a diagnosis. Clinical questions belong with a doctor.

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Curious what your DNA says?

Your browser reads your raw DNA file right on your device, so the file itself never leaves it. Out comes a personalized report you can read yourself or hand to your AI.

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