Honest comparison

A Sequencing.com alternative for the everyday side of your genome

Sequencing.com sells 30x whole genome sequencing from $399 and screens it for rare disease and carrier status, with genome plans at $129 a month on top. Helisoma does the everyday side: sleep, caffeine, food, training and mood. It reads your Sequencing.com VCF, or any chip file, in your browser for $49 once.

Free DNA analysis · $49 once for the full report · no subscription
Updated October 26, 2026. Prices checked on each company's own site.

What Sequencing.com does well

Depth and clinical focus. Sequencing.com reads 100% of your genome at 30x and screens it for rare disease, carrier status and medication response, which no chip test can do. You can download your FASTQ, BAM and VCF files at no extra cost, and uploading a chip file from another test is free.

Can I use my Sequencing.com data with Helisoma?

Yes. Download the VCF from your Sequencing.com account and drop it on Helisoma as it is, even at several gigabytes. Your browser reads it on your device and sends only the few hundred markers the report needs. The first findings are free, and the full report is $49 once. The download steps are on our whole genome page.

Where Helisoma is different

Sequencing.comHelisoma
What it costsWhole genome bundles $399, $599 and $999; Professional genome plan $129 a month$49 once, free analysis first, no subscription
What it focuses onRare disease, carrier screening, disease risk and medication responseSleep, caffeine, food, training, mood and longevity, each card with its study and effect size
Your DNA dataStored in your Sequencing.com account, which you can deleteRead in your browser, never uploaded
Files it readsIts own sequencing, plus chip files uploaded from other testsChip files from 23andMe, AncestryDNA, MyHeritage and FamilyTreeDNA, plus whole genome VCFs from Sequencing.com, Nebula and Dante Labs
Works with your AINo pairing with outside assistantsConnects to Claude and ChatGPT live, pairs with Gemini and Whoop Coach

Which one should you pick?

Pick Sequencing.com if you want a whole genome sequenced, or clinical-grade screening for rare disease, carrier status and medication response.

Pick Helisoma if you already have your genome or a chip file and want the everyday findings for $49 once, read on your device and answered through your own AI.

Also comparing? We compare against Promethease, SelfDecode, Genomelink, Nebula Genomics, Genetic Lifehacks and Xcode Life.

Questions people ask

How much does Sequencing.com cost?

As listed on its site in October 2026: whole genome bundles at $399, $599 and $999 (sale prices), and the Professional genome plan at $129 a month, billed annually. Uploading a chip file from another test is free. Helisoma is $49 once, and the first findings are free.

Does Helisoma read Sequencing.com whole genome files?

Yes. Drop the VCF from your Sequencing.com account as it is, gzipped or not, at any size. Your browser reads it on your device; raw reads (FASTQ, BAM, CRAM) are not needed and not supported.

Do I have to upload my raw DNA file to Helisoma?

No, and that is the core difference. Your browser reads the file on your own device and sends only the small set of markers the report uses. We never receive or store the raw file.

What does the Helisoma report cover?

Sleep and chronotype, caffeine response, nutrition markers, training and recovery, stress and mood leans, and longevity markers. Every card shows your genotype, the honest effect size, and a link to the study behind it.

How much does Helisoma cost?

The analysis is free: drop your raw DNA file on helisoma.com and see real insights with no account. The full report is a one-time $49 payment with no subscription.

Is Helisoma a medical test?

No. It is an educational wellness report built on peer-reviewed population research, not a diagnosis. Clinical questions belong with a doctor.

Guides from the blog

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Helisoma Report 23andMe · AncestryDNA · MyHeritage · FamilyTreeDNA

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